E-FABP, Human, pAb
Quantity
100 µg
Catalog #
HP9030-100UG
356,00 €
Verwandte Produkte
The polyclonal antibody recognizes human epidermal fatty acid binding protein (E-FABP) of both natural and recombinant origin. The E-FABP protein is derived from the human FABP5 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and seem to play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. E-FABP is localized in the skin.
| Quantity | 100 µg |
|---|---|
| Quantity | 100 µg |
| Formulation | 1 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide. |
| Application | Immuno assays, Paraffin sections, Western blot |
| Use | For Western blotting, dilution to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. |
| Isotype | Rabbit Ig |
| Cross reactivity | Mouse - Yes |
| Alias | FABP5, Psoriasis-associated fatty acid-binding protein homolog |
| References | 1. Veerkamp, J et al; Cytoplasmic fatty acid-binding proteins: their structure and genes. Prog Lipid Res 1995, 34: 17 2. Veerkamp, J et al; Stuctural and functional studies on different human FABP types. Mol Cell Biochem 1999, 192: 137 3. Fujii, K et al; Proteomic study of human hepatocellular carcinoma using two-dimensional difference gel electrophoresis with saturation cysteine dye. Proteomics 2005, 5: 1411 |
| Storage and stability | Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year. |
| Precautions | For research use only. Not for use in or on humans or animals or for diagnostics. It is the responsibility of the user to comply with all local/state and federal rules in the use of this product. Hycult Biotech is not responsible for any patent infringements that might result with the use or derivation of this product. |
| Disease | Autoimmunity, Tumor immunology |
| Application: | Immuno assays Paraffin sections Western blot |
|---|---|
| Use: | For Western blotting, dilution to be used depend on detection system applied. It is recommended that users test the reagent and determine their own optimal dilutions. The typical starting working dilution is 1:50. |