Nigericin (sodium salt) - HY-100381
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Catalog #
HY-100381
Ab
93,00 €
Nigericin sodium salt is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin sodium salt is a NLRP3 activator. Nigericin sodium salt shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/β-catenin signals. Nigericin sodium salt induces pyroptosis through caspase 1/GSDMD in TNBC[1][2][3][4][5][6][7].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-100381/Nigericin-sodium-salt-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | Cancer-programmed cell death |
| CAS | 28643-80-3 |
| Storage | 4°C (Powder, sealed storage, away from moisture) |
| MWT | 746.94 |
| Solubility | Ethanol : 25 mg/mL (ultrasonic) |
| Clinical Information | No Development Reported |
| Target | Antibiotic;Bacterial;NOD-like Receptor (NLR);Potassium Channel;Pyroptosis;Wnt;β-catenin |
| Application: | Cancer-programmed cell death |
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