Dolutegravir - HY-13238
Nur noch %1 verfügbar
Catalog #
HY-13238
Ab
57,00 €
Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC50 of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC50 of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC50=3.6-5.8 nM)[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-13238/Dolutegravir-DataSheet-MedChemExpress.pdf |
|---|---|
| Shipping | Room Temperature |
| Application | COVID-19-anti-virus |
| Alternative Names | S/GSK1349572 |
| CAS | 1051375-16-6 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 419.38 |
| Solubility | DMSO : 10 mg/mL (ultrasonic;warming) |
| Clinical Information | Launched |
| Target | HIV;HIV Integrase |
| Application: | COVID-19-anti-virus |
|---|