Gamcemetinib - HY-139504
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Catalog #
HY-139504
Ab
155,00 €
Gamcemetinib (CC-99677) is a potent, covalent, and irreversible inhibitor of the mitogen-activated protein (MAP) kinase-activated protein kinase-2 (MK2) pathway in both biochemical (IC50=156.3 nM) and cell based assays (EC50=89 nM). Gamcemetinib is extracted from patent WO2020236636, compound 1[1].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-139504/Gamcemetinib-DataSheet-MedChemExpress.pdf |
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| Shipping | Room Temperature |
| Application | COVID-19-immunoregulation |
| Alternative Names | CC-99677 |
| CAS | 1887069-10-4 |
| Storage | -20°C, 3 years; 4°C, 2 years (Powder) |
| MWT | 469.94 |
| Solubility | DMSO : 37.5 mg/mL (ultrasonic;warming;heat to 60°C) |
| Clinical Information | Phase 2 |
| Target | MAPKAPK2 (MK2) |
| Application: | COVID-19-immunoregulation |
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