Fz7-21 (TFA) - HY-P1454A
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Catalog #
HY-P1454A
Ab
227,00 €
Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC50 values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 TFA impairs the function of FZD7 in Wnt-β-catenin signalling and stem cell function in intestinal organoids[1][2].
| Datasheet URL | http://file.medchemexpress.com/batch_PDF/HY-P1454A/Fz7-21-TFA-DataSheet-MedChemExpress.pdf |
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| Shipping | Blue Ice |
| Application | Cancer-programmed cell death |
| Alternative Names | Ac-LPSDDLEFWCHVMY-NH2 (TFA) |
| Storage | -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture) |
| MWT | 1910.07 |
| Solubility | DMSO : 33.33 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL |
| Clinical Information | No Development Reported |
| Target | Wnt |
| Application: | Cancer-programmed cell death |
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